Space passions, revolutionary gene therapies, artificial intelligence, gravitational waves, black holes and 3D-printed organs you can actually touch. But also the chemistry of chocolate, the atlas of emotions, the 90th anniversary of Schrödinger’s cat and prehistoric reptiles brought back to life. Focus Live 2025, taking place from 7 to 9 November at the Museo Nazionale Scienza e Tecnologia Leonardo da Vinci in Milan (via Olona 4), will be an extraordinary journey across the many disciplines of science, where passion – this year’s theme – will be the common thread linking science, history, sport, art and music.
Over the course of three days, the festival organised by Focus magazine, under the patronage of the City of Milan, will offer visitors a chance to touch the future, experience the present of research and rediscover the passion that drives science. More than 120 guests, including astronauts, scientists, Olympic champions, artists and communicators, will meet the public in talks, workshops and live events.

Focus Live was created for those who aren’t satisfied with easy answers, for those who see the world with the eyes of an eternal explorer,” says Gian Mattia Bazzoli, Editor-in-Chief of Focus. “It’s a place where curiosity meets the experts shaping our tomorrow and where every question – even the most challenging – has its place. Here, a neurosurgeon can speak with a student, an astronaut answers children’s questions, and anyone can take part in experiments that usually happen only in labs. It’s our way of showing that science isn’t distant: we make it tangible, open to questions, even open to challenge. For three days, we transform the museum into a living laboratory for hands-on discovery and dialogue. For us at Focus, it’s the most genuine moment of the year – when we step out of pages and screens to connect directly with our readers and share our hunger for knowledge.”

The goal of this Festival of Knowledge by the Mondadori Group magazine is to explore the crucial role of science in shaping our future, presenting the achievements of human knowledge in an accessible and engaging way. It does so through authoritative voices, innovative formats and a mix of styles and disciplines – blending arts, music, nature, theatre and biology, sport and technology – revealing unexpected connections between them.

Focus Live – Passione, open to the public and completely free (with registration), will feature a rich programme of talks, workshops and performances hosted in the Cavallerizze area of the Museo Nazionale Scienza e Tecnologia Leonardo da Vinci, Italy’s largest science and technology museum, which for over 70 years has served as a bridge between the past and future of scientific culture.

To open this extraordinary edition, at 9:30 a.m. on Friday 7 November, Gian Mattia Bazzoli, Editor-in-Chief of Focus, will be joined by Fiorenzo Marco Galli, Director General of the National Museum of Science and Technology Leonardo da Vinci in Milan, and Carlo Mandelli, Chief Executive Officer of Mondadori Media.

The official opening will be led by Samantha Cristoforetti, ESA astronaut, who will share her “space passions”, the challenges of life in orbit, and how space research contributes to progress on Earth, helping us understand our planet and paving the way towards a more conscious and sustainable future. The festival will close on Sunday afternoon with astrophysicist Luca Perri, following a day featuring CERN physicist Guido Tonelli on the science of the void, journalist Beatrice Mautino on fighting misinformation, and science communicator Massimo Temporelli with his notebook of formulas explaining the Universe.

Between these moments, an extraordinary line-up will animate the Main Stage, Speakers’ Corner, Creators’ Corner, and the Kids Area curated by Focus Junior, offering activities and discussions designed to inspire curiosity and reflection.

The topics will be wide-ranging. Medicine will explore the promise of gene therapy with Luigi Naldini, Director of the San Raffaele Telethon Institute for Gene Therapy, who will explain how cutting-edge tools are used to fight rare diseases and cancers. The future of food will be explored by Luciano Pinotti and Enzo Spisni as they discuss novel foods and the challenges on our plates. Pierdomenico Perata, from the Scuola Superiore Sant’Anna in Pisa, will talk about the RNA revolution, while Patrick Gerlich from Bayer Crop Science Italia will present innovations in agriculture. On the tech front, Gian Maria Campedelli, scientist and criminologist, will show how AI can be used to fight organised crime, Tommaso Andreussi will explain how satellites might one day “breathe” Earth’s atmosphere, and researchers from the Italian Institute of Technology will introduce visitors to a real cyborg.

Olympic fencing champion Mara Navarria, gold medallist in Paris 2024, will talk with journalist Giorgio Terruzzi about what it takes to deliver a winning strike. Astrophysicist Amedeo Balbi will explore our cultural obsession with the apocalypse, while communicator Federico Taddia will “enter Einstein’s mind” with the help of a live illustrator. Neurosurgeon Christian Brogna will describe the marvels of awake brain surgery, joined on stage by one of his patients, who played the saxophone during the operation. Journalist Matteo Bordone and ethologist Monica Battini will challenge myths about cats, while Elio e le Storie Tese will deliver a humorous yet serious lesson on musical passion. Biotechnologist Marco Martinelli and the Subito team will engage the audience in a quiz about second-hand treasures.

Special moments will punctuate the festival: on Friday, representatives of Fondazione Milano Cortina 2026 will showcase the most iconic Olympic and Paralympic symbols, including torches, medals and mascots Tina and Milo. On Saturday afternoon, physicist Marcello Fanti will explore the Star Wars universe from a scientific perspective, joined by official Star Wars cosplayers from the Disney Lucasfilm-recognised 501st Italica Garrison (the “villains”), Rebel Legion Italian Base (the “heroes”) and the pink droid R2-KT. That same day, a group of Templar reenactors will demonstrate daily life and rituals from the medieval order. Finally, on Sunday, Gilberto Pichetto Fratin, Italy’s Minister for the Environment and Energy Security, will discuss energy transition. There will also be AI masterclasses, showing how to use artificial intelligence in everyday life, and the sweetest event of all: maître chocolatier Ernst Knam will take to the Main Stage to make chocolate live, revealing its fascinating chemistry and physics.

Experience Area

At Focus Live, science is not just something to watch or listen to — it is something to touch and do. The true heart of the Festival lies in the installations and workshops of the Experience Area, a multiverse of discovery where every corner promises a new adventure. The journey begins at the very dawn of time aboard the Big Bang Machine, a mobile installation (an enormous lorry) that takes visitors on a virtual odyssey back to the origins of the universe. Inside this space-time capsule, stars fuse, matter takes shape, and visitors learn how listening to cosmic signals is deeply connected to understanding our own planet. The exploration continues under the dome of an inflatable planetarium, where immersive films and live lectures unveil the secrets of the night sky. From there, a virtual leap transports visitors among the telescopes of the Cherenkov Telescope Array Observatory to chase the flashes of light emitted by black holes. Moving from the vast to the minute, the adventure shifts to the building blocks of life: visitors can extract DNA in a hands-on lab or imagine the future of medicine at the Humanitas University stand. The journey then heads south to Antarctica, where visitors can step inside a real polar field tent used by researchers from the University of Milano-Bicocca to drill ice cores — a rare chance to see the tools of extreme-environment research up close. Nearby, the micro-robots of the Sant’Anna School of Advanced Studies await, along with Supercalcolo, super passione, an interactive installation designed and produced by Amigdala.ch in collaboration with Eni.It explores the hidden world of supercomputing — the silent power driving science, industry, and everyday life. Here, every visitor can create a unique text and voice narrative in real time, co-authored with artificial intelligence. To discover how everyday habits affect our health, the AIRC Foundation will present its Prevention Labs, where playful games and quizzes reveal the risks of alcohol consumption, debunk myths, and show how smoking harms not only smokers and those around them but also the environment. The robot artist of the Università Cattolica will weave kilometres of thread to create striking portraits and images, while in the Outdoor Area (Open Air Lab) visitors can test themselves on an artificial climbing wall (powered by Grotte di Frasassi), an exciting challenge with both physical and mental benefits.

Immersion in the world of science and technology will also be ensured for Focus Live visitors thanks to the Museum’s rich resources. Each day, festival participants can book guided tours of the Leonardo Galleries and the Space Area, step into the shoes of a real astronaut at Base Marte, or try The Touch, the innovative sensory escape game that blends reality and virtuality in a Mars-themed adventure. The brand-new i.lab Sostenibilità will also be open, inviting visitors — through games, experiments and immersive installations — to explore what makes a product or an action truly sustainable, taking into account every element within its wider, interconnected system.

These are just some of the many experiences awaiting visitors at Focus Live, thanks to installations created by outstanding partners including Humanitas University, the Sant’Anna School of Advanced Studies, the Italian Institute of Technology, the AIRC Foundation, the Catholic University of Milan, and the Polytechnic University of Turin.

Kids’ area

For children and young people aged 2 to 13, the Kids Area — curated as always by Focus Junior — will be even richer this year, filled with STEM workshops, a dedicated stage for talks, and activities designed to help kids discover the wonders of science in a creative and surprising way.

From the science and math labs run by Mondadori Education to drawing workshops with Carioca products and Pokémon, every experience will be an adventure to live firsthand. In collaboration with the Kosmos Museum of Pavia, kids can take a dive into the past with the Oceani Perduti station and, guided by palaeontologists, handle original fossils and casts of ammonites, trilobites, and ancient marine reptiles, uncovering the stories hidden in the rocks. Grotte di Frasassi will amaze visitors with a VR Experience, while Jordan Oral Care will teach young explorers about the dentition of animals and the evolution of human teeth from prehistory to today. In the new “no Wi-Fi” play area, kids can take on challenges with Kapla wooden constructions, rediscovering the joy of analog play.

For the youngest visitors, children up to age 7, Focus Pico will offer workshops to draw, colour, and have fun. There will also be plenty of shows: on Friday, November 7, the day kicks off with a super quiz on sustainability and environmental awareness by Grotte di Frasassi. At 11:00 am, Fondazione AIRC will present its new science show Ricerca(ta) speciale, a journey through experiments, quizzes, and theatrical scenes. Saturday, November 8 at 12:00 pm, the acrobatic family Mr David & the Family will astonish audiences with their performances. On Sunday, November 9 at 4:00 pm, Geronimo and Tea Stilton will meet fans for a show about inventions. Throughout the weekend, artist Raffaele Salvoldi will guide children and adults in building fascinating Kapla structures, transforming imagination into real wooden architecture. Among the special guests, on Saturday at 3:00 pm, science communicator Gianumberto Accinelli will give a talk on the animal world. It’s a perfect chance to experience science as play, learn while having fun, and discover that knowledge can be the most thrilling adventure of all.

The Creators

As in the past three editions, Focus Live 2025 will host the Creators’ Corner, a stage where digital communicators bring science and culture to life on Instagram, TikTok, and YouTube.

This year, audiences will discover that the elements of the periodic table hide stories far more curious, and amusing, than one might think. Is it true, for instance, that drinking gold keeps you young forever? To answer that, there’s Eva Munter (@chimica_in_pillole). For those who’ve always dreaded math class, Professor Rocco Dedda (@unquartodoraconilprof) will share anecdotes that might just spark a passion for numbers. Giulia Ciccarelli (@medicina_in_cucina) and Giulia Biondi (@bilanciamo) will explain how to build a balanced menu, showing that eating is not just a necessity but a mix of culture, health, and well-being. Sara Figura (@laboratologia) will reveal the curiosities behind scientific research, while Silvia Casabianca (@madamstories) tackles a thought-provoking question: who really writes history? And that’s not all. Visitors will also meet the new faces of science communication, the top three finalists of FameLab Italia, the country’s first science communication talent competition, recently held in Perugia.

Special events

To enrich the schedule, as per tradition, on Friday 7 and Saturday 8 November at 8:30 pm, there will be two evening shows, free like all Focus Live events, combining entertainment, mystery, and, of course, science. Kicking off the 2025 special events, La scienza vista dal Basso will feature the hilarious Federico Basso hosting a live quiz that turns scientific curiosity and knowledge into an engaging game full of laughs and learning. On Saturday, the atmosphere turns thrilling with Delitto al museo, where Massimo Polidoro leads the audience through a crime scene set within the Leonardo da Vinci Museum. A captivating crime night showing how science, psychology, and the scientific method help investigators solve even the most complex cases. Two evenings, two different ways to experience science communication. Engaging, entertaining, and full of wonder.

The festival will close on Sunday at 6:30 pm with Luca Perri and Giacomo Moro Mauretto in La passione è un motore o un freno a mano?

Bookings

Event bookings can be made at www.focuslive.it There are two timeslots available: morning (10 am–2 pm) and afternoon (2 pm–8 pm). Those who wish to stay for the whole day can, of course, book tickets for both sessions.

Partners and sponsors

This edition of Focus Live is made possible through the collaboration and support of numerous institutions, research centres, and universities, including: ADMaiora, ASI, Business&Roads, European Gravitational Observatory (EGO), ESA, FBK, Human Technopole, IIT, INAF, Istituto Superiore Sant’Anna, JRC – Joint Research Centre, Kosmos, PLANit – Associazione dei Planetari Italiani, Politecnico di Torino, Smonting, Think About Science, Università Cattolica del Sacro Cuore, Università degli Studi di Milano, Università degli Studi di Milano-Bicocca, and Università degli Studi di Trieste.

Focus Live is a Mondadori Media event, organised in collaboration with the National Museum of Science and Technology Leonardo da Vinci and numerous partners.

MAIN PARTNERS: Eni, Ministry of the Environment and Energy Security
PARTNERS: Bayer, Grotte di Frasassi, Humanitas University, Jordan Oral Care, Subito, Toyota Motor Italia
CONTENT PARTNER: AIRC Foundation for Cancer Research, Mondadori Education
OFFICIAL RADIO: R101
In collaboration with the Cultural Olympiad of Milan Cortina 2026
AREA KIDS powered by Focus Junior
With the patronage of the City of Milan

The advertising for Focus Live is managed by Piemme S.p.A., the exclusive sales agency for Focus and other Mondadori Media brands.

The communication campaign and creative design of the event have been developed by Zampe Diverse, with production and organisational management by Left & Right.

The full Focus Live 2025 programme: Schedule: Focus Live 2025